CD57 Polyclonal Antibody, 100ul[BT-AP02083] Cellular Function Assays Mutations that result in the

Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia

resulting from alternative splicing and encoding different isoforms

This enzyme can be activated extracellularly by proteases

or it can bind with TAS1R2 to form a receptor for the sweet taste response

CD57 Polyclonal Antibody, 100ul[BT-AP02083] Cellular Function Assays Mutations that result in theCOL4A2 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, COL4A2 is organized in a head to head conformation with another type IV collagen gene so that each gene pair shares a common promoter.