Beclin-1(Phospho-Ser93) Rabbit Polyclonal Antibody, 50ul Cell Separation and Collection YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation

YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

Acting as a suppressor of RAS function

Several studies suggest that reduced serum concentrations of PSGs are associated with fetal growth restrictions| while up-regulation of this gene has been observed in colorectal cancers

Beclin-1(Phospho-Ser93) Rabbit Polyclonal Antibody, 50ul Cell Separation and Collection YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activationThis gene encodes a protein that regulates autophagy a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes including tumorigenesis neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.