TRIB3 Polyclonal Antibody, 50ul Pathway and Network Analysis The alpha-3 subunit lacks the

The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits

It is uncertain whether Met-1 or Met-4 is the initiator

UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons

miscellaneous:The N- and C-terminal domains are separated by a 2-repeat G-Q region

TRIB3 Polyclonal Antibody, 50ul Pathway and Network Analysis The alpha-3 subunit lacks theThe protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF kappaB. The encoded protein is a negative regulator of NF kappaB and can also sensitize cells to TNF and TRAIL induced apoptosis. In addition, this protein can negatively regulate the cell survival serine threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.