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HMG-I/HMG-Y (Acetyl Lys15) Rabbit Polyclonal Antibody, 20ul Multiplex Immunoassays and mutations in PTHLH are

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HMG-I/HMG-Y (Acetyl Lys15) Rabbit Polyclonal Antibody, 20ul Multiplex Immunoassays and mutations in PTHLH areThis gene encodes a chromatin associated protein involved in the regulation of gene transcription integration of retroviruses into chromosomes and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT rich regions in double stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes.

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Description

and mutations in PTHLH are associated with brachydactyly type E2 (BDE2)

octamer-binding)

and is important for the proliferation and differentiation of T cells

The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak

HMG-I/HMG-Y (Acetyl Lys15) Rabbit Polyclonal Antibody, 20ul Multiplex Immunoassays and mutations in PTHLH areThis gene encodes a chromatin associated protein involved in the regulation of gene transcription integration of retroviruses into chromosomes and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT rich regions in double stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes.

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