PHLD Polyclonal Antibody, 100ul Cellular Function Assays Phosphorylation by HIPK2 on Ser-422

Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation

The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt

and has been implicated in the pathogenesis of various malignancies and diseases of the immune system

Perfect for precise liquid transfers in scientific and medical settings

PHLD Polyclonal Antibody, 100ul Cellular Function Assays Phosphorylation by HIPK2 on Ser-422Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma