HBP1(Phospho Ser402) Polyclonal Antibody, 100ul Mechanical Pipette Mutations in this gene have

Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS)

which aids in transcriptional activation through interaction with RNA polymerase II and gene-specific transcription factors

a protein involved in the initiation of DNA replication

testis and colon

HBP1(Phospho Ser402) Polyclonal Antibody, 100ul Mechanical Pipette Mutations in this gene haveTranscriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5' TTCATTCATTCA 3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,Contains 1 AXH domain.,Contains 1 HMG box DNA binding domain.,subunit: Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4