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PLC Gamma1 Polyclonal Antibody, 100ul[BT-AP07260] Multiplex Immunoassays Mutations in this gene are

SKU: 91673093109

4.9
SEK141.00 SEK167.00

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PLC Gamma1 Polyclonal Antibody, 100ul[BT-AP07260] Multiplex Immunoassays Mutations in this gene areThe protein encoded by PLCG1 (phospholipase C gamma 1) catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate

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Description

Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency

and a C-terminal globular region

PH (Pleckstrin homology)

The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3

PLC Gamma1 Polyclonal Antibody, 100ul[BT-AP07260] Multiplex Immunoassays Mutations in this gene areThe protein encoded by PLCG1 (phospholipase C gamma 1) catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate

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