TRAPPC6A Polyclonal Antibody, 50ul Cell Transfection Receptor affinities are specified by

Receptor affinities are specified by variations in the 5'-end of the sequence

The expression of this receptor is induced by lymphocyte activation

The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis

and expansion of the number of repeats to 45-66 increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17

TRAPPC6A Polyclonal Antibody, 50ul Cell Transfection Receptor affinities are specified byTRAPPC6A (trafficking protein particle complex 6A) encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis Golgi membrane. Loss of expression of the related gene in mouse affects coat and eye pigmentation, suggesting that the encoded protein may be involved in melanosome biogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for TRAPPC6A.