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RB6I2 Polyclonal Antibody, 50ul Gene Synthesis Alternatively spliced transcript variants encoding

SKU: 91772372268

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RB6I2 Polyclonal Antibody, 50ul Gene Synthesis Alternatively spliced transcript variants encodingThe protein encoded by this gene is a member of a family of RIM binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10; 12)(q11; p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants.

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Description

Alternatively spliced transcript variants encoding different isoforms have been described for GRM8

which is resistant to high temperatures and high pressure

Mutations in this gene are associated with osteogenesis imperfecta types I-IV

When exposed to insulin| this protein is phosphorylated| dissociates from GLUT4 vesicles| resulting in increased GLUT4 at the cell surface| and enhanced glucose transport

RB6I2 Polyclonal Antibody, 50ul Gene Synthesis Alternatively spliced transcript variants encodingThe protein encoded by this gene is a member of a family of RIM binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10; 12)(q11; p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants.

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