GRK 2(Phospho Ser29) Polyclonal Antibody, 100ul DNA Fragments Tango1 subfamily

Tango1 subfamily

basic transcriptional factor and also as a bifunctional transcriptional regulator

The family members share a high degree of sequence identity| with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members

7 of which are encoded by the mitochondrial genome

GRK 2(Phospho Ser29) Polyclonal Antibody, 100ul DNA Fragments Tango1 subfamilyThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.