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CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries and pluripotency

SKU: 92168696982

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CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries and pluripotencyThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

and pluripotency

Mutations in this gene result in one form of autosomal dominant hearing impairment

a family of secreted chemorepellants

and three alternative downstream AUG initiation codons

CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries and pluripotencyThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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