Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 50ul Glassware Sets The Fo seems to have

The Fo seems to have nine subunits (a

the N-terminal region contains a polyglutamine tract of 14-31 residues that can be expanded in the pathogenic state to 32-200 residues

May be concerned with increased secretion of cytokines associated with cellular senescence

In response to DNA damage and replication blocks

Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 50ul Glassware Sets The Fo seems to haveATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis