SH-PTP2 Polyclonal Antibody, 20ul[BT-AP08302] Syringe Filter An important paralog of this

An important paralog of this gene is DNAL4

It also contains a destruction box (D box) that is required for its degradation by the APC

Cullin 3 plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex

and are clustered together on chromosome X

SH-PTP2 Polyclonal Antibody, 20ul[BT-AP08302] Syringe Filter An important paralog of thisTyrosine protein phosphatase non receptor type 11 encoded by PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology 2 domains, which function as phospho tyrosine binding domains and mediate the interaction of this PTP with its