CD6 Polyclonal Antibody, 100ul[BT-AP01912] Cell Dissociation Mutations in this gene may

Mutations in this gene may be associated with congenital aural atresia syndrome

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum

RCF: 15100×g

which suggests active roles in meiotic and mitotic recombination

CD6 Polyclonal Antibody, 100ul[BT-AP01912] Cell Dissociation Mutations in this gene mayThe protein encoded by CTSL is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha 1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein (cathepsin L) has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular