Histone H3(Phospho Thr32) Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Mutations in this gene may

Mutations in this gene may be associated with adult-onset sensorimotor neuropathy

The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks

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Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas

Histone H3(Phospho Thr32) Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Mutations in this gene mayHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin