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PBF Polyclonal Antibody, 50ul Drug Development and Evaluation Additional variants have been observed|

SKU: 93099363913

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PBF Polyclonal Antibody, 50ul Drug Development and Evaluation Additional variants have been observed|PTTG1IP (pituitary tumor transforming 1 interacting protein) encodes a single pass type I integral membrane protein, which binds to pituitary tumor transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for PTTG1IP.

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Description

Additional variants have been observed| but their full-length natures have not been determined

This gene is expressed mainly in testis with weak expression in the brain

Working in a complementary fashion

The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein

PBF Polyclonal Antibody, 50ul Drug Development and Evaluation Additional variants have been observed|PTTG1IP (pituitary tumor transforming 1 interacting protein) encodes a single pass type I integral membrane protein, which binds to pituitary tumor transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for PTTG1IP.

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