sMtCK Monoclonal Antibody, 50ul Recombinant Ab Production SIGLEC8 is a member of

SIGLEC8 is a member of the CD33-like subgroup of SIGLECs

It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis

Dysregulation of this gene has been associated with the growth and progression of certain cancers

An important paralog of this gene is FPR2

sMtCK Monoclonal Antibody, 50ul Recombinant Ab Production SIGLEC8 is a member ofMitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase