REPS2 Polyclonal Antibody, 50ul Vacuum Filter The encoded preproprotein is proteolytically

The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone

Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia

possibly as a result of compromised regulatory T cell recruitment

but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme

REPS2 Polyclonal Antibody, 50ul Vacuum Filter The encoded preproprotein is proteolyticallyThe product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.