DBLOH Polyclonal Antibody, 20ul Cellular Function Assays Required for nuclear receptor-mediated transactivation

Required for nuclear receptor-mediated transactivation

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins

thus differing from the other known gene family members

mouse NLRP3 shares 78% and 93% aa identity with human and rat NLRP3

DBLOH Polyclonal Antibody, 20ul Cellular Function Assays Required for nuclear receptor-mediated transactivationThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript