GRK 2(Phospho Ser685) Polyclonal Antibody, 100ul Sampling Tubes Defects in this gene are

Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30)

Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation

and homeostasis by coupling chromatin remodeling to transcription factor recognition

CCNB1 and CDKN1A

GRK 2(Phospho Ser685) Polyclonal Antibody, 100ul Sampling Tubes Defects in this gene areThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.