CLN3 Polyclonal Antibody, 20ul Stepper Cleavage occurs at the

Cleavage occurs at the

Contains 5 C2HC-type zinc fingers

Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype

which catalyze the exchange of bound GDP for GTP

CLN3 Polyclonal Antibody, 20ul Stepper Cleavage occurs at theThis gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.