LC3A Rabbit Polyclonal Antibody, 50ul DNA Libraries Synthesis mutations in this gene are

mutations in this gene are thought to confer a predisposition to sarcomas

This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins

but they have not been thoroughly characterized

This protein is a component of anaphase-promoting complex (APC)

LC3A Rabbit Polyclonal Antibody, 50ul DNA Libraries Synthesis mutations in this gene areProbably involved in formation of autophagosomal vacuoles (autophagosomes). PTM: The precursor molecule is cleaved by APG4B ATG4B to form the cytosolic form LC3 I. This is activated by APG7L ATG7 transferred to ATG3 and conjugated to phospholipid to form the membrane bound form LC3 II. Belongs to the MAP1 LC3 family. subcellular location: LC3 II binds to the autophagic membranes. subunit: 3 different light chains LC1 LC2 and LC3 can associate with