LKB1(Phospho Thr189) Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Mutations in PFKM have been

Mutations in PFKM have been associated with glycogen storage disease type VII

hepatocellular carcinomas

kidney and skeletal muscle

The protein encoded by this gene is found in both mitochondria and the nucleus| where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters

LKB1(Phospho Thr189) Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Mutations in PFKM have beenThis gene, which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not