UNC5D Polyclonal Antibody, 20ul Yeast Expression Mutations in HGF are associated

Mutations in HGF are associated with nonsyndromic hearing loss

This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene

Additional alternatively spliced transcript variants of this gene have been described| but their full-length nature is not known

and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors

UNC5D Polyclonal Antibody, 20ul Yeast Expression Mutations in HGF are associatedReceptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.,PTM: Phosphorylated on cytoplasmic tyrosine residues.,PTM: