PROF1 Polyclonal Antibody, 50ul Gloves Autoantibodies reacting with this protein

Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus

Serves as a positive regulator of erythroid differentiation

DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family

Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D)

PROF1 Polyclonal Antibody, 50ul Gloves Autoantibodies reacting with this proteinThis gene encodes a member of the profilin family of small actin binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.