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MAGE-9 Polyclonal Antibody, 100ul Lysosome but this phenotype is not

SKU: 9490214884

4.3
EUR123.75 EUR166.75

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MAGE-9 Polyclonal Antibody, 100ul Lysosome but this phenotype is notMAGEA9 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary

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Description

but this phenotype is not causally related to neurologic disease

Mutations in this gene have been associated with microencephaly| cortical malformations| and mental retardation

The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin

Specifically represses the transcription of the CDKN2A gene

MAGE-9 Polyclonal Antibody, 100ul Lysosome but this phenotype is notMAGEA9 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary

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