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Granuphilin Polyclonal Antibody, 50ul Multiplex Immunoassays Different cyclins exhibit distinct expression

SKU: 95133135107

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Granuphilin Polyclonal Antibody, 50ul Multiplex Immunoassays Different cyclins exhibit distinct expressionSYTL4 (synaptotagmin like 4) encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N terminal Rab27 binding domain and C terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript

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Description

Different cyclins exhibit distinct expression and degradation patterns

A recent study showed this gene to be an authentic stop codon readthrough target| and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon

Defects in this gene lead to metachromatic leucodystrophy (MLD)

Loss of function or expression of this gene has been detected in multiple tumors

Granuphilin Polyclonal Antibody, 50ul Multiplex Immunoassays Different cyclins exhibit distinct expressionSYTL4 (synaptotagmin like 4) encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N terminal Rab27 binding domain and C terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript

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