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p53 Polyclonal Antibody, 100ul[BT-AP06808] Peptide Library This small gene family is

SKU: 95395298935

4.1
SEK123.75 SEK160.75

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p53 Polyclonal Antibody, 100ul[BT-AP06808] Peptide Library This small gene family isTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains

which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane

the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63

This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD)

p53 Polyclonal Antibody, 100ul[BT-AP06808] Peptide Library This small gene family isTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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