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ARHG8 Polyclonal Antibody, 100ul Glassware Sets Contactin-1 encoded by CNTN1 is

SKU: 95914402882

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ARHG8 Polyclonal Antibody, 100ul Glassware Sets Contactin-1 encoded by CNTN1 isThis gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants

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Description

Contactin-1 encoded by CNTN1 is a member of the immunoglobulin superfamily

Binding of its ligand| hepatocyte growth factor| induces dimerization and activation of the receptor| which plays a role in cellular survival| embryogenesis| and cellular migration and invasion

Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain

It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina| and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle

ARHG8 Polyclonal Antibody, 100ul Glassware Sets Contactin-1 encoded by CNTN1 isThis gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants

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