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CD6 Polyclonal Antibody, 20ul[BT-AP01846] Molecular Weight Markers and reduction in gene expression

SKU: 96097416099

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PLN97.20 PLN145.20

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CD6 Polyclonal Antibody, 20ul[BT-AP01846] Molecular Weight Markers and reduction in gene expressionClaudin 4 encoded by this intronless gene (CLDN4) belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre and postnatal life. This gene is

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Description

and reduction in gene expression was shown in colorectal cancers (PMID: 17982127)

breast cancer

the N-terminal regulatory domain that is processed upon calpain activation

and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction

CD6 Polyclonal Antibody, 20ul[BT-AP01846] Molecular Weight Markers and reduction in gene expressionClaudin 4 encoded by this intronless gene (CLDN4) belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre and postnatal life. This gene is

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