CD70 Polyclonal Antibody, 20ul[BT-AP07445] Bio-Reaction Tube The encoded mechanosensing protein contains

The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension| resulting in the reconfiguration of cadherin-actin filament connections

A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling

Defects in APC cause familial adenomatous polyposis (FAP)

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CD70 Polyclonal Antibody, 20ul[BT-AP07445] Bio-Reaction Tube The encoded mechanosensing protein containsThe protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27 CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B cell activation,