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MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix Mutations in this gene are

MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix Mutations in this gene are

Name: MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix Mutations in this gene are
Brand: schmucketriebe.at
SKU: 96119748835
Price: 185.00 USD
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SKU: 96119748835

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MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix Mutations in this gene areMucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007

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Description

Mutations in this gene are a cause of colorectal cancer (CRC)

consisting of KRTHB1

This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin

It contains a Sec7 domain

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