MIB2 Polyclonal Antibody, 50ul Yeast Expression calcification

calcification

POLD3 encodes the 66-kDa subunit of DNA polymerase delta

In humans| this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes

Transcript variants encoding different isoforms have been identified for this gene

MIB2 Polyclonal Antibody, 50ul Yeast Expression calcificationE3 ubiquitin protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.,induction: Down regulated in many primary skin melanomas. Treatment with a demethylating agent, 5' aza 2 deoxycytidine, restores expression, suggesting that down regulation is the result