IL-17R Alpha Polyclonal Antibody, 50ul[BT-AP04454] Bio-Reaction Tube Mutations at this locus have

Mutations at this locus have been linked to autosomal recessive deafness

It has been reported that there may be several pseudogenes on chromosomes 1

In the mid-region of the protein| family members have a proline-rich domain that binds SH3 and WW domain-containing proteins

The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions

IL-17R Alpha Polyclonal Antibody, 50ul[BT-AP04454] Bio-Reaction Tube Mutations at this locus haveInterleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T lymphocytes. It is a potent inducer of the maturation of CD34 positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and