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MYLK Polyclonal Antibody, 20ul[BT-AP05707] Modified Oligos Inhibits SIRT1 in a CHEK2

SKU: 96790940340

4.5
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MYLK Polyclonal Antibody, 20ul[BT-AP05707] Modified Oligos Inhibits SIRT1 in a CHEK2MYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. MYLK encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein

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Description

Inhibits SIRT1 in a CHEK2 and PSEM3-dependent manner and inhibits the activity of CHEK2 in vitro (PubMed: 25361978)

The encoded preproprotein is proteolytically processed to generate the mature peptidase

The encoded preproprotein (cathepsin D) is proteolytically processed to generate multiple protein products

The coating on the surface is firm and convenient for daily experimental operation

MYLK Polyclonal Antibody, 20ul[BT-AP05707] Modified Oligos Inhibits SIRT1 in a CHEK2MYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. MYLK encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein

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