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RASL2 Polyclonal Antibody, 100ul Site-directed Mutagenesis Its expression is up-regulated in

SKU: 96845622729

4.4
PLN123.75 PLN143.75

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RASL2 Polyclonal Antibody, 100ul Site-directed Mutagenesis Its expression is up-regulated inThis gene encodes a member of the GAP1 family of GTPase activating proteins that suppresses the Ras mitogen activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP bound state to the inactive GDP bound state and no longer activates downstream

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Description

Its expression is up-regulated in some types of cancer

Phosphorylation of Ser-122 is strongly stimulated by hypoxia

metastasis

Binding of YWHAZ inhibits DNA-binding

RASL2 Polyclonal Antibody, 100ul Site-directed Mutagenesis Its expression is up-regulated inThis gene encodes a member of the GAP1 family of GTPase activating proteins that suppresses the Ras mitogen activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP bound state to the inactive GDP bound state and no longer activates downstream

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