MARCH2 Polyclonal Antibody, 100ul Recombinant Protein This intronless gene is deleted

This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome

Gene Ontology (GO) annotations related to this gene include transporter activity and transmembrane transporter activity

Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP

RHOA encodes a member of the Rho family of small GTPases

MARCH2 Polyclonal Antibody, 100ul Recombinant Protein This intronless gene is deletedMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.