MKX Polyclonal Antibody, 50ul Gene Editing Represses the ligand-dependent transcriptional activation

Represses the ligand-dependent transcriptional activation function of ESR2 (PubMed: 20074560)

Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation| and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization

It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols

Therefore| the encoded protein is thought to be an important part of functional kinetochores

MKX Polyclonal Antibody, 50ul Gene Editing Represses the ligand-dependent transcriptional activationThe protein encoded by this gene is an IRX family related homeobox protein that may play a role in cell adhesion. Studies in mice suggest that this protein may be a regulator of tendon development. Two transcript variants encoding the same protein have been found for this gene.