Human Toll-like Receptor 1, TLR1 ELISA Kit , 96T Tubes The protein localizes to actin-rich

The protein localizes to actin-rich structures including membrane ruffles| microvilli| and filopodia

which may contribute to vitamin A-directed differentiation in epithelial tissue

Belongs to the IFRD family

|Contains 1 acyl carrier domain

Human Toll-like Receptor 1, TLR1 ELISA Kit , 96T Tubes The protein localizes to actin-richParticipates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed: 21078852). Forms the activation cluster TLR2: TLR1: CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid raft