TOPRS Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) the full-length nature is known

the full-length nature is known for some but not all of the variants

ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences

2000 [PubMed 10888605])

Mutations in this gene have been associated with microencephaly| cortical malformations| and mental retardation

TOPRS Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) the full-length nature is knownThis gene encodes a nuclear protein which is serine and arginine rich, and contains a RING type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus.