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p53(Phospho-Ser366) Polyclonal Antibody, 50ul Custom RNA Oligos Substrate of the antigen receptor-coupled

SKU: 99482726547

4.4
USD185.00 USD207.00

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p53(Phospho-Ser366) Polyclonal Antibody, 50ul Custom RNA Oligos Substrate of the antigen receptor-coupledThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Substrate of the antigen receptor-coupled tyrosine kinase

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer

COL2A1 encodes the alpha-1 chain of type II collagen

Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN)

p53(Phospho-Ser366) Polyclonal Antibody, 50ul Custom RNA Oligos Substrate of the antigen receptor-coupledThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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