Integrin Beta4 Polyclonal Antibody, 50ul[BT-AP04591] Culture Tubes Mutations in this gene result

Mutations in this gene result in cataract congenital nuclear autosomal recessive type 2

As part of the SNARE complex| it is required for vesicle docking and fusion and regulates neurotransmitter release

The protein encoded by this gene is a member of kinesin-like protein family

Two alternatively spliced transcript variants encoding different isoforms are described for this gene

Integrin Beta4 Polyclonal Antibody, 50ul[BT-AP04591] Culture Tubes Mutations in this gene resultIntegrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand binding specificities. Integrins mediate cell matrix or cell cell adhesion, and transduced signals that regulate gene expression and cell growth. ITGB4 encodes Integrin beta 4, a receptor for the laminins. This subunit