KLHL3 Polyclonal Antibody, 50ul Subcellular Fractions exon 4 encodes the transmembrane

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KLHL3 Polyclonal Antibody, 50ul Subcellular Fractions exon 4 encodes the transmembraneKLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N terminal BTB domain followed by a BACK domain and six kelch like repeats in the C terminus. These kelch like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare

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