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ZN195 Rabbit Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Studies of the Drosophila counterpart

SKU: 9981233771

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ZN195 Rabbit Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Studies of the Drosophila counterpartThis gene encodes a protein belonging to the Krueppel C2H2 type zinc finger protein family. These family members are transcription factors that are implicated in a variety of cellular processes. This gene is located near the centromeric border of chromosome 11p15. 5 next to an imprinted domain that is associated with maternal specific loss of heterozygosity in Wilms' tumors. Alternative splicing results in multiple transcript variants.

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Description

Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL| as well as with COPS5/JAB1| a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP

Overexpression of this gene is associated with glioblastoma

The protein encoded by this gene is involved in antigen presentation

neuron differentiation

ZN195 Rabbit Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Studies of the Drosophila counterpartThis gene encodes a protein belonging to the Krueppel C2H2 type zinc finger protein family. These family members are transcription factors that are implicated in a variety of cellular processes. This gene is located near the centromeric border of chromosome 11p15. 5 next to an imprinted domain that is associated with maternal specific loss of heterozygosity in Wilms' tumors. Alternative splicing results in multiple transcript variants.

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