NEIL3 Polyclonal Antibody, 100ul RNA Synthesis PGR uses two distinct promotors

PGR uses two distinct promotors and translation start sites in the first exon to produce several transcript variants

and seminiferous tubules

Since this protein is not capable of binding DNA directly

Three transcript variants encoding two different proteins have been found for this gene

NEIL3 Polyclonal Antibody, 100ul RNA Synthesis PGR uses two distinct promotorsNEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.