CLLU1 Rabbit Polyclonal Antibody, 100ul Bottles The protein encoded by DDX3Y

The protein encoded by DDX3Y (DEAD-box helicase 3

Nuclear RanGTP concentration is maintained through nuclear localization of guanine nucleotide exchange factor (GEF) activity

disease:Defects in GRN are the cause of ubiquitin-positive frontotemporal dementia (UP-FTD)

MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al

CLLU1 Rabbit Polyclonal Antibody, 100ul Bottles The protein encoded by DDX3YThe protein encoded by this gene is overexpressed in chronic lymphocytic leukemia (CLL) and serves as a good prognostic marker for the disease. Methylation of certain genes including this one have been associated with CLL. This gene is protein coding in humans and non protein coding in other primates. Three transcript variants one protein coding and the other two non protein coding have been found for this gene.