Ezatiostat Hydrochloride Size:Solid 10 mg GNF-2 dose-dependently inhibited the proliferation

GNF-2 dose-dependently inhibited the proliferation of osteoclast precursors through the suppression of the M-CSFR c-Fms

ETC-159 has robust activity in multiple cancer models driven by high Wnt signaling

6-dinitro-4-(trifluoromethyl)phenyl]amino}-1-(4-fluorophenyl)thiourea

Chemical Name: 4-{3-[(1E)-2-[(3-bromophenyl)carbamoyl]-2-cyanoeth-1-en-1-yl]-2

Ezatiostat Hydrochloride Size:Solid 10 mg GNF-2 dose-dependently inhibited the proliferationEzatiostat is a liposomal small molecule glutathione analog inhibitor of glutathione S transferase (GST) P1 1 with hematopoiesis stimulating activity. After intracellular de esterification, the active form of ezatiostat binds to and inhibits GST P1 1, thereby restoring Jun kinase and MAPK pathway activities and promoting MAPK mediated cellular proliferation and differentiation pathways. This agent promotes the proliferation and maturation of