Exatecan Mesylate - CAS# 169869-90-3 noprol Smiles: N#CC1C(=O)NC2SC=C(C=2C=1O)C1C=CC(=CC=1)C1=CC=CC=C1O

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Exatecan Mesylate - CAS# 169869-90-3 noprol Smiles: N#CC1C(=O)NC2SC=C(C=2C=1O)C1C=CC(=CC=1)C1=CC=CC=C1OExatecan Mesylate, CAS No. 169869 90 3, also known as DX 8951, is semisynthetic, water soluble camptothecin derivative with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater

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