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SB-269970 Hydrochloride - CAS# 261901-57-9 oprenaline Hydrochloride 0 nM against MDA-MB-231 cell

SB-269970 Hydrochloride - CAS# 261901-57-9 oprenaline Hydrochloride 0 nM against MDA-MB-231 cell

Name: SB-269970 Hydrochloride - CAS# 261901-57-9 oprenaline Hydrochloride 0 nM against MDA-MB-231 cell
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SKU: 16808351116
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SKU: 16808351116

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SB-269970 Hydrochloride - CAS# 261901-57-9 oprenaline Hydrochloride 0 nM against MDA-MB-231 cellSB269970 HCl is a potent 5 HT7A antagonist (pKi = 8. 9) that demonstrates >50 fold binding selectivity over 5 HT5A and >250 fold selectivity over 5 HT1, 5 HT2, 5 HT4, 5 HT6, adrenergic 1, dopamine D2, and dopamine D3 receptors. It is also reported to block adrenergic 2 receptors in guinea pig vas deferens. SB 269970 has been used to target the 5 HT7 receptor in the study of schizophrenia like cognitive deficits. Product information CAS Number: 261901

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Description

0 nM against MDA-MB-231 cell line

In the mouse xenograft models using subcutaneously transplanted UM-UC-14 and MGHU3

CAS Number: 50700-72-6

compared to the Cat S inhibitor LHVS (IC50=0

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