EXP3174 - CAS# 124750-92-1 Catalog No.:M6459-2 CAS Number: 1222800-79-4

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EXP3174 - CAS# 124750-92-1 Catalog No.:M6459-2 CAS Number: 1222800-79-4EXP3174, also known as Losartan Carboxylic Acid, CAS No. 124750 92 1, is a physiologically active metabolite of losartan, produced by cytochrome P450 isoforms in the liver. Like the parent compound, EXP3174 is a potent AT1 antagonist (Kis = 0. 57 and 0. 67 nM for rat and human forms, respectively), producing a depressor response and vasodilatation. When administered intravenously, losartan carboxylic acid is more potent and has a longer duration of

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